SE that persists despite first- and second-line agents requires anesthetic induction (e.g., Propofol , Midazolam infusion , or Ketamine ) and continuous EEG monitoring. 5. Prognosis and Challenges
Airway, breathing, circulation (ABC) and blood glucose check. Status Epilepticus: A Clinical Perspective
Status Epilepticus: A Clinical Perspective Status Epilepticus (SE) is a critical neurological emergency characterized by prolonged seizure activity or recurrent seizures without a return to baseline consciousness. This paper explores the evolving definitions of SE, its pathophysiological mechanisms, and current clinical management strategies. With a focus on the "time is brain" paradigm, we examine the transition from early SE to refractory and super-refractory stages, highlighting the importance of rapid intervention to prevent permanent neuronal damage and systemic complications. 1. Introduction SE that persists despite first- and second-line agents
If seizures persist, non-sedative anti-seizure medications (ASMs) such as Levetiracetam , Fosphenytoin , or Valproate are administered. 1. Introduction If seizures persist