Sloppy -
The primary foundational paper for this concept is , which provides a comprehensive review of the framework. Key Scientific Papers on Sloppiness
(Transtrum et al., 2015): A definitive review describing the information theoretic framework based on the Fisher Information Matrix (FIM).
: Researchers use the FIM to measure how distinguishable models are based on their predictions. In sloppy models, FIM eigenvalues are distributed roughly evenly over many decades.
(Gutenkunst et al., 2007): Demonstrates that sloppiness is a universal feature in systems biology, suggesting that modelers should focus on predictions rather than exact parameter values.
The primary foundational paper for this concept is , which provides a comprehensive review of the framework. Key Scientific Papers on Sloppiness
(Transtrum et al., 2015): A definitive review describing the information theoretic framework based on the Fisher Information Matrix (FIM).
: Researchers use the FIM to measure how distinguishable models are based on their predictions. In sloppy models, FIM eigenvalues are distributed roughly evenly over many decades.
(Gutenkunst et al., 2007): Demonstrates that sloppiness is a universal feature in systems biology, suggesting that modelers should focus on predictions rather than exact parameter values.