Cristina treats a man with type II diabetes who loses his foot, a case she uses to mirror the "dying" state of her own relationship with Burke. 🛑 Major Character Developments

Hector Elizondo makes his first appearance as Carlos Torres. He is initially skeptical of George but later expresses respect for George’s desire to provide for Callie independently. 🎵 Trivia & Soundtrack

The episode (Season 3, Episode 19) of Grey's Anatomy originally aired on March 22, 2007. It is best known for the fallout of George and Izzie's controversial night together and the high-stakes interviews for the Chief of Surgery position. 🏥 Medical Cases & Guests

Izzie remembers sleeping with George, but George is initially too hungover to recall. He later has a flashback during a lunch with Callie's father.

Before her breakout role in Mad Men , Moss guest-starred as Nina Rogerson, the daughter and caretaker of the FOP patient.

Callie treats a patient with a rare genetic condition where muscle tissue is replaced by bone.

Alex helps "Jane Doe" (Elizabeth Reaser) choose a new face from a series of portraits. One of the photo options shown was actually a photo of the actress herself, Elizabeth Reaser.