A standard Mexicanism meaning "it doesn't matter" or "never mind". "Aunque": The Spanish word for "although" or "even if".
The phrase gained significant fame through the 1983 song by Los Traileros del Norte . The lyrics revolve around a man who remains devoted to his partner despite her conditions or unfulfilled promises, repeating the phrase to emphasize his stubborn acceptance. No Le Hace Que Le Aunque
The full expression often includes the follow-up: "al cabo que con que" . This further doubles down on the wordplay, using "con que" (meaning "with what" or "as long as") to create a rhyming, circular sentiment that emphasizes a "don't worry about it" attitude. A standard Mexicanism meaning "it doesn't matter" or