The series dates back to , when Louisiana (then SLI) dominated with a 66-0 victory. Since then, the momentum has swung heavily; while Louisiana won the first seven meetings, Southern Miss has historically controlled the series, winning 42 of the next 48 games following 1930. Recent matchups have been high-stakes "spoilers":
: Louisiana previously snapped a losing streak against Southern Miss with a 23-13 win to open their 2024 Sun Belt campaign. The Quest for "Link 3" The series dates back to , when Louisiana
: The defining moment of that 2025 game was a record-breaking 98-yard touchdown pass from Braylon Braxton to Micah Davis, the longest pass play in Golden Eagles history. The Quest for "Link 3" : The defining
: On October 18, 2025, Southern Miss spoiled Louisiana’s homecoming in Lafayette with a 22-10 win . The series dates back to