While many Slug-knockout mice are viable, studies demonstrate its essential role in pigment formation, hematopoietic stem cells, and germ cells.
mSlug is a transcription factor that plays a critical role in developmental EMT, neural crest cell migration, and cancer progression. While many Slug-knockout mice are viable
Slug and Snail are repressors that mediate the EMT process. hematopoietic stem cells
It is often activated by stem cell factor c-kit signaling and is necessary for migrating cells. 3. Materials and Methods for mSlug Analysis neural crest cell migration
mSlug (Slugh/Snail2) is used to study epithelial-mesenchymal transitions.