Missions take players across the globe, including fighting through a flooded city in the Philippines, rescuing hostages in the Somali Coast, and tactical operations in Pakistan.

The game follows —specifically Preacher and Mother —as they track a new, incredibly dangerous explosive, PETN (Pentaerythritol tetranitrate).

PETN is a high-grade explosive capable of bypassing airport security. Terrorists are distributing it worldwide, setting up a global, imminent threat.

Following a devastating attack in Madrid that puts Preacher in a coma (and kills civilians, including a key target), the team converges for a final, intense raid on Hassan's compound in Pakistan, where he is ultimately killed by Preacher and Voodoo. The Human Side: The Price of Deployment