S16e16: Grey's Anatomy

While calling former colleagues to gather support for Meredith’s medical license hearing (earlier in the season), Alex reached out to Izzie .

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s. Grey's Anatomy s16e16

Season 16, Episode 16 of Grey's Anatomy , titled serves as the official farewell to original cast member Justin Chambers , who played Dr. Alex Karev . The episode aired on March 5, 2020, and is one of the most controversial in the series' history due to how it handles Alex's departure. ✉️ The Core Format: Letters from Alex While calling former colleagues to gather support for

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction Alex Karev

He apologizes for leaving via a letter and reveals he is filing for divorce. He leaves her his shares in Grey Sloan Memorial Hospital.

Alex claims that while he still loves Jo , he cannot bear to let his children grow up without a father the way he did. He is now living on a farm in Kansas where Izzie works as a surgical oncologist. ⚡ Secondary Storylines