The title "Boa Me" translates to "Help Me" in Twi. The song's lyrics focus on:

One of the most notable features of the track is Ed Sheeran singing exclusively in Twi, a major dialect spoken in Ghana. His proficiency in the language was widely praised by Ghanaian audiences upon the song's release.

The track was born from a spontaneous creative session at Fuse ODG's house in Accra, Ghana, where it was written and recorded in approximately two hours. Produced by the award-winning KillBeatz , the song follows the success of "Bibia Be Ye Ye" from Ed Sheeran's Divide album, which the pair also collaborated on during Sheeran's 2016 trip to Ghana.