The title refers to a standard prison sentence for murder, but Eminem applies it to his career in several ways:
He mentions her being jealous when he spends time with his daughters. Eminem Feat Namolla Family - 25 To Life
He implies he is serving time because he "killed" (dominated) the competition. 🎤 Key Lyrics & Context The title refers to a standard prison sentence
He complains about how he dresses ("baggy sweats") just to please her. Eminem Feat Namolla Family - 25 To Life
He feels "imprisoned" by the demands of the rap game.