If your game is 32-bit, the x64 version will not work. You must use the 32-bit (x86) version of x360ce instead.
The program will likely warn you that xinput1_3.dll (or a similar file) is missing. Click Create to let the app generate the necessary translation files. Download x360ce x64 zip
Once you have downloaded the zip file, follow these steps to get your controller working: If your game is 32-bit, the x64 version will not work