CME6 stands for , a gameplay modification for Doom (specifically designed for source ports like Zandronum or GZDoom). It focuses on:

: Typically refers to a specific "flavor" or sub-mod (potentially the "Knot Edition") that adds even more complex mechanics, rare weapon drops, or specific balance changes popularized by the CME community.

: Overhauling AI and adding new enemy types to provide a more challenging experience than the original game.

: Likely refers to a version of the mod that keeps the weapon and item set standard or balanced for traditional Doom levels.