Takes about 30–60 minutes to start working, peaks in 2–4 hours, and lasts up to 8 hours.

While more affordable, OTC insulins act differently than newer, rapid-acting prescription analogs like Humalog or Novolog: Over-the-Counter Insulin: What to Know Before You Buy

A premixed combination of 70% NPH and 30% Regular. Where to Buy and Cost

OTC insulin is legally sold in 49 states and the District of Columbia. Indiana , which previously required a prescription for all insulin, removed this restriction in 2021. Important Safety Considerations

CVS Pharmacy offers similar options for around the same price through its Reduced Rx program .

Takes 2–4 hours to start working, peaks in 4–12 hours, and lasts 12–18 hours.