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DHEA is most effective when treating documented hormone deficiencies or specific medical issues rather than as a general wellness supplement:

: In women with diminished ovarian reserve, some studies suggest DHEA may improve egg quality, increase pregnancy rates, and lower miscarriage risks when taken under medical supervision for 6–12 weeks before IVF. buy dhea supplement

: Some evidence indicates it may be "possibly effective" for improving mood in people with low DHEA levels, though it is not a first-line therapy. DHEA is most effective when treating documented hormone