Agent: Alkalating

The primary goal of these agents is to disrupt the DNA replication process. They achieve this through a process called :

Alkylating agents are a critical class of chemotherapy drugs that act directly on the DNA of cells to prevent them from growing and dividing. Unlike many other cancer treatments, they are , meaning they can attack cancer cells at any stage of their life cycle. How They Work alkalating agent

: Bifunctional agents can link two DNA bases together (interstrand or intrastand cross-linking), which prevents the DNA strands from separating for replication. The primary goal of these agents is to

: The drug attaches an "alkyl group" to a DNA base, most frequently at the N7 position of guanine . alkalating agent