287_63 Apr 2026

: It is a triazole-based modification of alginate, specifically created through "click chemistry" to change the surface properties of the polymer.

: In animal models, 287_63 was identified as one of the top-performing "anti-fibrotic" materials. It significantly reduced the formation of scar tissue around implants. 287_63

This molecule was part of a large library of triazole-modified alginates developed by researchers at MIT and Boston Children's Hospital. The goal was to find a coating that would allow implanted medical devices or encapsulated cells (like those used for Type 1 Diabetes treatment) to function inside the body without being attacked by the immune system. Key Findings for 287_63 : It is a triazole-based modification of alginate,

: Highly cited papers in Nature Medicine and Nature Biotechnology (circa 2016) by the Anderson and Langer labs. This molecule was part of a large library